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85 FengN.FengY.TanJ.ZhouC.XuJ.ChenY.et al (2023)
109 MoonS
Most patients tolerate peptide therapy very well
Mechanistic themes seen in preclinical research In animal and mechanistic work, AOD-9604 has been associated with: Increased lipolysis (breaking down stored fat) Reduced lipogenesis (reducing fat storage) Interactions with -adrenergic pathways in adipose tissue have been discussed as part of its lipolytic signaling profile (OUP Academic) In obese animal models, AOD-9604 has shown reductions in body weight and body fat and changes consistent with increased fat mobilization
Hydroxyproline and glucuronic acid were used as indicators of collagen and GAG content, respectively
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